Opportunity Information: Apply for CDC RFA GH19 1919
The grant opportunity titled "Strengthening the Delivery of and Expanding Access to Quality Laboratory Services and Laboratory Safety in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)" is a U.S. government funding announcement focused on improving laboratory systems that support HIV, tuberculosis (TB), and related infectious disease programs in South Africa. Issued by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), this notice of funding opportunity (NOFO) is designed to strengthen the overall delivery of laboratory services, expand access to high-quality testing, and make laboratory operations safer and more effective. In practical terms, the effort centers on ensuring that patients and clinics can reliably access accurate test results and that those results are used quickly and correctly to guide treatment decisions, which is essential for HIV/TB control.
A major emphasis of the NOFO is improving the quality and reach of laboratory services across the country, including strengthening systems that link clinics to laboratories. That clinic-laboratory interface is critical because even strong laboratory testing capacity does not translate into better patient outcomes if samples are not transported efficiently, results do not return to clinicians promptly, or clinicians do not act on results. By focusing on uptake and use of laboratory results, the opportunity signals an interest not only in running tests, but also in improving the full diagnostic pathway: ordering, specimen collection, specimen referral, testing, result reporting, and clinical follow-up. This type of work commonly involves streamlining processes, reducing turnaround times, improving result delivery mechanisms, and supporting better communication and coordination between facility staff and laboratory services.
Another core component is laboratory safety. The NOFO explicitly calls for improving laboratory safety practices, which generally includes strengthening biosafety and biosecurity measures, reinforcing safe handling and disposal of infectious materials, ensuring proper use of personal protective equipment, and promoting adherence to safety standards and quality management systems. In settings where laboratories handle high volumes of HIV and TB samples, and where TB in particular poses airborne transmission risks, stronger safety systems protect laboratory workers, health care workers, and the broader community while also reducing disruptions that can occur when safety incidents compromise operations.
The opportunity also highlights strengthening the quality of point-of-care (POC) testing for HIV/TB and related infections. Point-of-care testing refers to diagnostic testing conducted near the patient (for example, in clinics rather than centralized laboratories), which can speed up clinical decisions and reduce loss to follow-up. However, POC testing only improves outcomes when it is implemented with strong quality assurance, proper training, consistent supply chains, instrument maintenance, and reliable data capture and reporting. By calling out POC quality specifically, the NOFO indicates support for the systems that make decentralized testing trustworthy and programmatically useful, rather than simply increasing the number of testing devices.
This is described as a follow-on NOFO, meaning it is intended to continue or build upon existing work rather than start from scratch. The CDC office in South Africa plans to continue collaborative engagement with the National Health Laboratory Service (NHLS), the key public laboratory network in South Africa. The aim is to develop and implement activities that align with both PEPFAR-South Africa priorities and the South African government goals for HIV, TB, and other opportunistic infectious diseases. In other words, the work is meant to fit into national strategies and strengthen local systems, with NHLS positioned as a central partner for implementation and sustainability.
From an administrative and funding standpoint, the opportunity is listed as discretionary funding and uses a cooperative agreement mechanism. A cooperative agreement usually implies substantial involvement by the CDC during implementation, such as collaboration on technical direction, monitoring, and programmatic decision-making. The NOFO is identified as CDC RFA GH19-1919, with CFDA number 93.067, under a health funding activity category. The posted award ceiling is $8,000,000, and the CDC anticipated making one award, suggesting a single primary recipient or lead implementing partner responsible for coordinating the work at scale.
The NOFO was created on August 30, 2018, with an original closing date of October 30, 2018. Applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date. Eligibility is described broadly as "Others," with additional eligibility details referenced in the full announcement text, which typically clarifies what types of organizations may apply and any specific requirements.
Overall, the grant is aimed at strengthening the laboratory backbone of South Africa's HIV/TB response under PEPFAR by improving access to quality testing, ensuring results move efficiently from labs to clinics and are acted upon, raising laboratory safety standards, and reinforcing the quality systems needed for reliable point-of-care diagnostics. The structure and scale of funding indicate a focused, nationally significant effort carried out in close coordination with NHLS and aligned with both U.S. PEPFAR objectives and South Africa's public health priorities.Apply for CDC RFA GH19 1919
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening the Delivery of and Expanding Access to Quality Laboratory Services and Laboratory Safety in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Aug 30, 2018.
- Applicants must submit their applications by Oct 30, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $8,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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